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6 OMIM references -
6 associated genes
3 signs/symptoms
PROTEIN INTERACTIONS: 1
COMMON SIGNS: 1
1 OMIM reference -
1 associated gene
10 signs/symptoms
Neuroblastoma
Papilloma of choroid plexus

ALK TP53
HACE1
LIN28B
MYCN
PHOX2B
TOP2A


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
TOP2A
(0.88)
TP53



Citations in the biomedical literature:


Neuroblastoma
ALK HACE1 LIN28B MYCN PHOX2B TOP2A

Papilloma of choroid plexus
TP53



Neuroblastoma
Papilloma of choroid plexus

Synonym(s):
- Neural crest tumor
- Sympathoblastoma

Synonym(s):
(no synonyms)

Classification (Orphanet):
- Rare neurologic disease
- Rare oncologic disease
Classification (Orphanet):
- Rare neurologic disease
- Rare oncologic disease

Classification (ICD10):
- Neoplasms -
Classification (ICD10):
- Neoplasms -

Epidemiological data:
Class of prevalence: 1-5 / 10 000
Average age onset: childhood
Average age of death: child / adolescent
Type of inheritance: sporadic
Epidemiological data:
(no data available)

External references:
6 OMIM references -
2 MeSH references: C536408 / D009447
External references:
1 OMIM reference -
1 MeSH reference: D020288


COMMON
SIGNS
- Central nervous system / peripheral nerves neoplasm / tumor / carcinoma / cancer


Neuroblastoma
Papilloma of choroid plexus

Very frequent
- Organic acid metabolism anomalies

Frequent
- Autosomal dominant inheritance



Very frequent
- Autosomal recessive inheritance
- Hydrocephaly
- Structural anomalies of the nervous system

Occasional
- Hemiplegia / diplegia / hemiparesia / limb palsy
- Hypertonia / spasticity / rigidity / stiffness
- Intellectual deficit / mental / psychomotor retardation / learning disability
- Mild visual loss / impaired visual acuity
- Neoplasms / tumors
- Seizures / epilepsy / absences / spasms / status epilepticus